Primary Identifier | MGI:3770133 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Slc4a3 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacing most of exon 6, intron 6, the cardiac-specific first exon and promoter, and exon 7 with a neomycin resistance gene. Expression of both the cardiac specific- short isoform and the long isoform of the gene were eliminated in homozygote mice as determined by western blots of retinal extracts. |