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Allele : Saa3<em1Capi> serum amyloid A 3; endonuclease-mediated mutation 1, Carol Pilbeam

Primary Identifier  MGI:6199070 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Saa3
Strain of Origin  CD-1 Is Recombinase  false
Is Wild Type  false
molecularNote  Two in-frame nonsense mutations (TAA and TGA) were introduced into exon 1 using an sgRNA and a template oligonucleotide with CRSIPR/Cas9 technology. This mutation creates a p.L14X (p.Leu14Stop) mutation resulting in a severely truncated open reading frame.
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele