Primary Identifier | MGI:2429762 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 216724 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable SH2 domain binding activity; SH3 domain binding activity; and identical protein binding activity. Acts upstream of or within protein transport; regulation of endocytosis; and small GTPase-mediated signal transduction. Located in cytoplasm. Is expressed in brain; genitourinary system; heart; liver; and lung. Orthologous to human RUFY1 (RUN and FYVE domain containing 1). PHENOTYPE: Mice heterozygous for a knock-out allele show normal methamphetamine-induced locomotor activity. [provided by MGI curators] |