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Publication : Molecular cloning of a cDNA for rat TM4SF4, a homolog of human il-TMP (TM4SF4), and enhanced expression of the corresponding gene in regenerating rat liver(1).

First Author  Liu Z Year  2001
Journal  Biochim Biophys Acta Volume  1518
Issue  1-2 Pages  183-9
PubMed ID  11267677 Mgi Jnum  J:68364
Mgi Id  MGI:1932609 Doi  10.1016/s0167-4781(01)00170-1
Citation  Liu Z, et al. (2001) Molecular cloning of a cDNA for rat TM4SF4, a homolog of human il-TMP (TM4SF4), and enhanced expression of the corresponding gene in regenerating rat liver(1). Biochim Biophys Acta 1518(1-2):183-9
abstractText  il-TMP (also known as TM4SF4) is a human tetraspanin that is expressed in human intestine and liver. We have cloned a novel cDNA for a rat gene with sequence similar to that of a cDNA for human il-TMP. The cDNA encoded a protein of 202 amino acids, designated rat TM4SF4. The corresponding transcript was detected in rat liver and testis. The expression of rat TM4SF4 was enhanced in regenerating liver after two-thirds partial hepatectomy. It was supposed that rat TM4SF4 might play a role in cell proliferation and in liver regeneration.
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