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Allele : Nfkb2<tm1Sbn> nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; targeted mutation 1, Ulrich Siebenlist
Primary Identifier  MGI:2179705 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfkb2
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced sequences encoding the dimerization/DNA binding domain, the nuclear translocation sequence and the first seven ankyrin domains. Western blot analysis on lysates derived from spleen of homozygous mice confirmed that no detectable isoform of the encoded protein was present.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Nfkb2-,
  • p52/p100-,
  • NF-kappaB/p52 null,
  • Nfkb2-,
  • NF-kappaB/p52 null,
  • p52/p100-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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