| Primary Identifier | IPR030521 | Type | Family |
| Short Name | SH2B1 |
| description | SH2B adapter protein 1 (SH2B1) belongs to the SH2B family of adapter proteins []. It promotes insulin expression and glucose metabolism in beta-cells in mice []. It is also involved in brain-derived neurotrophic factor-induced neurite outgrowth [].SH2B family contains three members of adaptor proteins: SH2B1, 2 and 3 []. Typical SH2B proteins contain a SH2 (Src homology 2) and a PH (pleckstrin homology) domain. They serve as adaptors involved in signalling by the receptors for growth factors, such as insulin-like growth factor 1, platelet-derived growth factor and nerve growth factor []. |
