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Allele : Cetn2<tm1.1Wbae> centrin 2; targeted mutation 1.1, Wolfgang Baehr

Primary Identifier  MGI:5634782 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cetn2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Mice carrying the Cetn2tm1Wbae allele were crossed with an EIIa-Cre driver to eliminate the neo cassette and delete exons 2 and 3. Truncated mRNA (encompassing exons 1, 4, and 5) was detectable by RT/PCR but at very low levels (5-10% of wild-type). The truncated protein was undetectable in mutant olfactory epithelia by immunostaining, indicating that this is a null allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cetn2<deltaEx2,3>,
  • Cetn2<deltaEx2,3>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele