| Primary Identifier | IPR034367 | Type | Family |
| Short Name | VASP |
| description | Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity, such as axon guidance and lamellipodial and filopodial dynamics in migrating cells [, ]. Ena/VASP proteins possess a modular domain organization, including a conserved tetramerization domain (TD) mediates the formation of Ena/VASP tetramers []. In vertebrates there are three Ena-VASP family members: Mena (Mammalian enabled), VASP, and EVL (Ena-VASP like).Vasodilator-stimulated phosphoproteins (VASP) is one of the founding members of the Ena/VASP family. VASP promotes actin nucleation and increases the rate of actin polymerisation in the presence of capping protein []. |
