| Primary Identifier | MGI:3041167 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 330890 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables piRNA binding activity. Involved in retrotransposon silencing; secondary piRNA processing; and spermatogenesis. Acts upstream of with a positive effect on retrotransposon silencing by heterochromatin formation. Located in nucleus and piP-body. Is expressed in embryo; germ cell of testis; testis; and trunk unsegmented mesenchyme. Orthologous to human PIWIL4 (piwi like RNA-mediated gene silencing 4). PHENOTYPE: Mice homozygous for a null allele exhibit male specific-infertility with a progressive loss of male germ cells, reduced testis size, abnormal male meiosis and increased apoptosis of spermatocytes in seminiferous tubules. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
