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Allele : Tg(Camk2a-PLA2G4A)31Mrl transgene insertion 31, Merck Research Laboratory

Primary Identifier  MGI:6434525 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Camk2a-PLA2G4A)31Mrl
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgenic construct contains 5Ž the 8.5 kb mouse CaM-kinase II alpha chain (mCamk2a) promoter fragment, an 850 bp DNA fragment containing the human beta-globin intron 2, and 2247bp ORF of human PLA2G4A cDNA (GenBank Acc# NM_024420), followed by 221bp of SV40 poly A sequence at the 3Ž end in a pGL3 vector backbone (Promega). A consensus KOZAK sequence was added upstream of the starter ATG.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele