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Type  MGI:General Description  in resident-intruder test, individually tested male isolated for 1, 5 or 21 days mice show reduced frequency and duration of consummate and ambivalent aggression towards an intruder in the resident animal's cage after 30 days in isolation, male mutants do not show increased consummate aggression towards other animals when placed together, in contrast to wild-type males which show high levels of aggression towards other males mutants show a greater duration of defensive behavior after 30 days of isolation than wild-type males