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Allele : Cdk6<tm2.1Phin> cyclin dependent kinase 6; targeted mutation 2.1, Philip Hinds

Primary Identifier  MGI:5141514 Allele Type  Targeted
Gene  Cdk6 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 1 was replaced with one in which nucleotide substitutions result in the amino acid substitution of cystine for arginine at position 31 (R31C). A floxed stop cassette downstream of the modified exon 1 that prevents expression was removed by cre-mediated recombination. The product is predicted to be a hyperactivate kinase.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Cdk6<R31C>,
  • Cdk6<R31C>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele