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Protein Coding Gene : Brf2 BRF2, RNA polymerase III transcription initiation factor 50kDa subunit
Primary Identifier  MGI:1913903 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  66653
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity and TBP-class protein binding activity. Predicted to be involved in DNA-templated transcription initiation; cellular response to oxidative stress; and regulation of transcription by RNA polymerase III. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Predicted to be active in nucleus. Orthologous to human BRF2 (BRF2 RNA polymerase III transcription initiation factor subunit).
  • synonyms:
  • Brf2,
  • AU022602,
  • MGI:1919827,
  • expressed sequence AU018504,
  • MGI:2142706,
  • BRFU,
  • RIKEN cDNA 5730512K07 gene,
  • 5730512K07Rik,
  • TFIIIB50,
  • AU018504,
  • expressed sequence AU022602,
  • RIKEN cDNA 2700059M06 gene,
  • BRF2, RNA polymerase III transcription initiation factor 50kDa subunit,
  • MGI:2142684,
  • 2700059M06Rik
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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4 Pathways

Trail: ProteinCodingGene

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Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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