Primary Identifier | IPR002017 | Type | Repeat |
Short Name | Spectrin_repeat |
description | Spectrin repeats are found in several proteins involved in cytoskeletal structure and in proteins with a more regulatory role mostly in animals [, ]. This entry includes spectrin alpha and beta subunits, alpha-actinin and dystrophin [, , ]. The spectrin repeat forms a three-helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteristic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. |