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Protein Coding Gene : P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6

Primary Identifier  MGI:2673874 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  233571
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables G protein-coupled UDP receptor activity. Acts upstream of or within cellular response to organic cyclic compound; cellular response to prostaglandin E stimulus; and transepithelial chloride transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in dermomyotome and musculature. Orthologous to human P2RY6 (pyrimidinergic receptor P2Y6).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal macrophage, endothelial, and vascular smooth muscle response to UTP and UDP. [provided by MGI curators]
  • synonyms:
  • P2ry6,
  • 2010204J23Rik,
  • pyrimidinergic receptor P2Y, G-protein coupled, 6,
  • MGI:1913795,
  • P2Y6,
  • RIKEN cDNA 2010204J23 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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