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Allele : Hbb-b1<MommeD7> hemoglobin, beta adult major chain; modifier of murine metastable epialleles, D7

Primary Identifier  MGI:3821597 Allele Type  Chemically induced (ENU)
Gene  Hbb-b1 Inheritance Mode  Dominant
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  ENU induced a T to C substitution at position 757 in the mRNA altering the canonical polyadenylation signal. Northern blot analysis on RNA from fetal liver cells from homozygous and heterozygous mice detected reduced expression of the wild-type transcript and the presence of larger RNA species not seen in wild-type samples.
  • mutations:
  • Single point mutation
  • synonyms:
  • RBC14,
  • RBC14
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories