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Publication : Cloning, tissue expression, and chromosomal assignment of human MRJ gene for a member of the DNAJ protein family.

First Author  Seki N Year  1999
Journal  J Hum Genet Volume  44
Issue  3 Pages  185-9
PubMed ID  10319584 Mgi Jnum  J:55223
Mgi Id  MGI:1337516 Doi  10.1007/s100380050139
Citation  Seki N, et al. (1999) Cloning, tissue expression, and chromosomal assignment of human MRJ gene for a member of the DNAJ protein family. J Hum Genet 44(3):185-9
abstractText  The DnaJ protein family consists of proteins with a highly conserved amino acid stretch called the J-domain. A cDNA clone encoding a new protein with a J-domain was isolated from a human fetal brain cDNA library. This new member of the DnaJ family of 241 amino acid residues showed 94% identity with mouse Mrj (accession number, AF035962) and 71% identity with mouse Msj-1 (accession number, U95607) along its entire sequence. Reverse transcription-coupled polymerase chain reaction (RT-PCR) analysis showed the messenger RNA was ubiquitously expressed in various human tissues. The chromosomal location of the gene was determined by PCR-based analyses with both a human/rodent monochromosomal hybrid cell panel and a radiation hybrid panel to map on chromosome 11q25 region.
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