| Primary Identifier | IPR004004 | Type | Family |
| Short Name | Helic/Pol/Pept_Calicivir-typ |
| description | Caliciviruses are positive-stranded ssRNA viruses that cause gastroenteritis []. The calicivirus genome contains two open reading frames, ORF1 and ORF2 [, ]. ORF1 encodes a non-structural polypeptide, which has RNA helicase, cysteine protease and RNA polymerase activity. The cysteine peptidases of the Calciviruses belong to MEROPS peptidase families C3 (subfamilies A to G), C24, C28, C37 and C40. The regions of the poly-protein in which these activities lie are similar to proteins produced by the picornaviruses [, ]. |
