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Allele : Ikbkb<tm1Mka> inhibitor of kappaB kinase beta; targeted mutation 1, Michael Karin

Primary Identifier  MGI:1857769 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ikbkb
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = GS (Genome Systems).
molecularNote  A neomycin resistance cassette replaced part of the second and the entire third coding exon of the gene, which encodes for a part of the kinase domain of the protein. Western blots of protein extracts from embryonic fibroblasts from homozygous mutant mice showed no detectable protein for the targeted gene.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IKKbeta-,
  • IKKbeta-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

15 Publication categories

Trail: Allele