Primary Identifier | MGI:1857769 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ikbkb |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = GS (Genome Systems). |
molecularNote | A neomycin resistance cassette replaced part of the second and the entire third coding exon of the gene, which encodes for a part of the kinase domain of the protein. Western blots of protein extracts from embryonic fibroblasts from homozygous mutant mice showed no detectable protein for the targeted gene. |