| Primary Identifier | MGI:2385915 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Bves |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A cassette containing NLS-lacZ and neo genes was inserted downstream of the translational start codon in exon 2 via homologous recombination. Normal transcript was undetected by RT-PCR analysis of heart, skeletal muscle, and bladder tissue obtained from homozygous mutant mice. Although the 5' UTR and all intronic sequences were left intact, the expression of beta-galactosidase did not completely correlate with that of the endogenous gene. |
