| Primary Identifier | IPR034609 | Type | Family |
| Short Name | Syce2 |
| description | The synaptonemal complex (SC) is a tripartite structure that physically links homologous chromosomes during prophase I. The SC has a zipper-like structure composed of two lateral elements (LEs) and a central element (CE). Transverse filaments, composed of SYCP1 molecules, bridge the gap between one LE and the CE.Syce2/CESC1 localises to the CE and interacts with the transverse filament protein SYCP1. Its localization to the CE is dependent on recruitment by SYCP1 []. Syce2/ CESC1 is required for synaptonemal complex assembly and also for double strand break repair and homologous recombination []. |
