| First Author | Erdmann D | Year | 1995 |
| Journal | Undersea Hyperb Med | Volume | 22 |
| Issue | 4 | Pages | 395-9 |
| PubMed ID | 8574127 | Mgi Jnum | J:30372 |
| Mgi Id | MGI:77885 | Citation | Erdmann D, et al. (1995) Skin allograft rejection and hyperbaric oxygen treatment in immune-histoincompatible mice. Undersea Hyperb Med 22(4):395-9 |
| abstractText | The effect of hyperbaric oxygen (HBO) as an immunosuppressive agent was evaluated by using a highly immunogenic skin allograft mouse model. Immune-histoincompatible female C57BL/6 and BALB/c mice (N = 30) were randomly assigned to three groups receiving no treatment (control group), low dose HBO treatment (two treatments once a week), and intermediate HBO treatment (two treatments 3 times/wk) 1 wk before and 2 wk after transplantation of a 1.5 x 2 cm full thickness skin allograft from the back. Rejection was observed a Day 7 and was completed 14 days after surgery in controls. Low dose and intermediate HBO treatment delayed skin allograft rejection, which was histologically confirmed. |
