| First Author | Chicheportiche Y | Year | 1994 |
| Journal | J Biol Chem | Volume | 269 |
| Issue | 8 | Pages | 5512-7 |
| PubMed ID | 8119883 | Mgi Jnum | J:16950 |
| Mgi Id | MGI:65007 | Doi | 10.1016/s0021-9258(17)37490-2 |
| Citation | Chicheportiche Y, et al. (1994) Cloning and expression of a mouse macrophage cDNA coding for a membrane glycoprotein of the scavenger receptor cysteine-rich domain family. J Biol Chem 269(8):5512-7 |
| abstractText | We have cloned from murine macrophages a cDNA coding for a new protein of the scavenger receptor family whose mRNA is increased very strongly by adherence and moderately by exposure to tumor necrosis factor and interferon-gamma. The nucleotidic sequence extends for 2168 bases and encodes a protein of 559 amino acids with six potential glycosylation sites. The first 100 NH2-terminal amino acids represent a single scavenger receptor cysteine-rich domain, whereas the COOH-terminal end of the molecule is compatible either with a transmembrane hydrophobic peptide followed by a very short intracytoplasmic sequence or a signal sequence for an anchoring via a glycophosphatidylinositol. The protein is highly homologous to most of the very recently identified human MAC-2-binding protein and murine cyclophilin C-associated protein. |
