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Protein Coding Gene : Trim62 tripartite motif-containing 62

Primary Identifier  MGI:1914775 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  67525
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in positive regulation of antifungal innate immune response. Acts upstream of or within negative regulation of epithelial to mesenchymal transition. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; maxillary process; sensory organ; and submandibular gland primordium. Orthologous to human TRIM62 (tripartite motif containing 62).
PHENOTYPE: Mice heterozygous or homozygous for a targeted allele exhibit increased tumorigenesis. [provided by MGI curators]
  • synonyms:
  • Dear1,
  • Trim62,
  • 6330414G21Rik,
  • tripartite motif-containing 62,
  • RIKEN cDNA 6330414G21 gene,
  • MGI:2140291,
  • AI450348,
  • expressed sequence AI450348

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For