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Allele : Prph2<tm1.1Naash> peripherin 2; targeted mutation 1.1, Muna I Naash
Primary Identifier  MGI:5818812 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Prph2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT site and loxP site flanked neomycin resistance gene cassette was inserted into intron 1 and exon 1 was replaced with a version with two engineered mutations: a silent TTC>TTT mutation to aid genotyping and an AAA deletion to create an allele coding for a peptide with a K153 deletion. This deletion emulates one causing variable retinal phenotypes in human patients. The neo cassette was removed through flp-mediated recombination.
  • mutations:
  • Intergenic deletion,
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Prph2<Kdelta>,
  • Prph2<Kdelta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

6 Publication categories

Trail: Allele




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