Primary Identifier | MGI:2158741 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Chrne |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A genomic fragment containing part of exon 7 and exon 8 was replaced with a neomycin selection cassette. These sequences encode essential regions for the function of the protien. RT-PCR experiments on RNA derived from muscle tissue of homozygous mice demonstrated that no detectable levels of wild-type transcript were produced from this allele. |