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Allele : Chrne<tm1Vwi> cholinergic receptor, nicotinic, epsilon polypeptide; targeted mutation 1, Veit Witzemann

Primary Identifier  MGI:2158741 Allele Type  Targeted
Attribute String  Null/knockout Gene  Chrne
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing part of exon 7 and exon 8 was replaced with a neomycin selection cassette. These sequences encode essential regions for the function of the protien. RT-PCR experiments on RNA derived from muscle tissue of homozygous mice demonstrated that no detectable levels of wild-type transcript were produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • AChRepsilon -,
  • AChRepsilon -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele