First Author | Coppola T | Year | 1994 |
Journal | FEBS Lett | Volume | 338 |
Issue | 1 | Pages | 1-5 |
PubMed ID | 8307146 | Mgi Jnum | J:16589 |
Mgi Id | MGI:64658 | Doi | 10.1016/0014-5793(94)80105-3 |
Citation | Coppola T, et al. (1994) Molecular cloning of a murine N-type calcium channel alpha 1 subunit. Evidence for isoforms, brain distribution, and chromosomal localization. FEBS Lett 338(1):1-5 |
abstractText | A cDNA encoding a N-type Ca2+ channel has been cloned from the murine neuroblastoma cell line N1A103. The open reading frame encodes a protein of 2,289 amino acids (257 kDa). Analysis of different clones provided evidence for the existence of distinct isoforms of N-type channels. High levels of mRNA were found in the pyramidal cell layers CA1, CA2 and CA3 of the hippocampus, in the dentate gyrus, in the cortex layers 2 and 4, in the subiculum and the habenula. The N-type Ca2+ channel gene has been localized on the chromosome 2, band A. |