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Allele : Sprtn<tm1Yjm> SprT-like N-terminal domain; targeted mutation 1, Yuichi J Machida
Primary Identifier  MGI:5752649 Allele Type  Targeted
Attribute String  Hypomorph Gene  Sprtn
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Progeria (J:225198)
molecularNote  A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. RT-PCR confirmed reduced transcript expression due to the cryptic exon in the neomycin resistance cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Sprtn<H>,
  • Sprtn<neo>,
  • Sprtn<neo>,
  • Sprtn<H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

5 Publication categories

Trail: Allele




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