Primary Identifier | MGI:5752869 | Allele Type | Targeted |
Gene | Dnmt1 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A nucleotide was inserted in the 5' end of exon 13 and an exon was deleted from the 3' end of exon 13, altering the amino acids across the exon encoding the conserved and mouse rat differential regions of the intrisically disordered domain (IDD). Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of exon 12. |