|  Help  |  About  |  Contact Us

Protein Coding Gene : Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform

Primary Identifier  MGI:99878 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  19042
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Enables phosphoprotein phosphatase activity. Acts upstream of or within cellular response to transforming growth factor beta stimulus; negative regulation of BMP signaling pathway; and positive regulation of protein export from nucleus. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including Peyer's patch; brain; ganglia; male reproductive gland or organ; and white fat. Orthologous to human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit delayed wound healing, delayed re-epithelialization, and decreased keratinocyte migration. [provided by MGI curators]
  • synonyms:
  • 2900017D14Rik,
  • Ppm1a,
  • MGI:1920167,
  • MGI:1916736,
  • MPPa-1,
  • MMPa-2,
  • expressed sequence AU017636,
  • Mpp alpha,
  • AU017636,
  • MGD-MRK-16669,
  • AI427932,
  • MGI:2144943,
  • 2310003C21Rik,
  • RIKEN cDNA 2900017D14 gene,
  • RIKEN cDNA 2310003C21 gene,
  • protein phosphatase 1A, magnesium dependent, alpha isoform,
  • expressed sequence AI427932,
  • MGI:2144816

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For