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Protein Coding Gene : Ppp1r8 protein phosphatase 1, regulatory subunit 8

Primary Identifier  MGI:2140494 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  100336
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables protein phosphatase regulator activity. Acts upstream of or within cell population proliferation. Predicted to be located in nucleoplasm. Predicted to be part of spliceosomal complex. Predicted to be active in nuclear speck. Is expressed in adrenal gland and brain. Orthologous to human PPP1R8 (protein phosphatase 1 regulatory subunit 8).
PHENOTYPE: Embryos homozygous for knock-out allele exhibit severe growth retardation and impaired cell proliferation and die between embryonic days 6.5 and 7.5. [provided by MGI curators]
  • synonyms:
  • expressed sequence AU044684,
  • NIPP1,
  • protein phosphatase 1, regulatory subunit 8,
  • Ppp1r8,
  • 6330548N22Rik,
  • RIKEN cDNA 6330548N22 gene,
  • AU044684

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For