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Protein Coding Gene : Slc12a8 solute carrier family 12 (potassium/chloride transporters), member 8

Primary Identifier  MGI:2443672 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  171286
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable potassium:chloride symporter activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Is expressed in lateral hypothalamic area and metanephros. Orthologous to human SLC12A8 (solute carrier family 12 member 8).
PHENOTYPE: Mice homozygous for a null allele exhibit some prenatal lethality and reduced NAD+ levels in the jejunum and ileum. [provided by MGI curators]
  • synonyms:
  • solute carrier family 12 (potassium/chloride transporters), member 8,
  • RIKEN cDNA E330020C02 gene,
  • E330020C02Rik,
  • Slc12a8

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Genome

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For