| Primary Identifier | MGI:3040693 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 328365 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable SMAD binding activity; SUMO ligase activity; and nuclear receptor coactivator activity. Involved in positive regulation of Notch signaling pathway and positive regulation of T cell differentiation. Acts upstream of or within several processes, including circulatory system development; positive regulation of fibroblast proliferation; and vitellogenesis. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including early embryo; embryo ectoderm; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human ZMIZ1 (zinc finger MIZ-type containing 1). PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality during organogenesis with failure of yolk sac vascular remodeling and abnormal embryonic vascular development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
