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Type  MGI:General Description  platelets incubated with arachidonic acid generate less 12-hydroxyeicosatetraenoic acid and more polar products relative to control platelets at a higher concentration of arachidonic acid, however homozygotes are healthy and fertile, show no increase in sensitivity to hyperoxia, have no abnormalities in the brain, heart, intestine, kidney, liver, lung, and spleen, and have normal numbers of total blood cells, red cells, reticulocytes, lymphocytes, monocytes, neutrophils, eosinophils, and platelets