| Type | MGI:General | Description | at P60, bright field imaging revealed that a ring-like demarcation between the cortical and nuclear fiber cells is absent in most mutant lenses, unlike in control lenses at P30, SEM analysis showed that deep into the lens tissue mutant lenses display cortical fiber cell morphology in place of nuclear fibers at P0, wheat germ agglutinin (WGA) staining revealed a significantly reduced lens nucleus region relative to controls, suggesting fiber cell nuclear compaction defects at E12.5, E14.5 and E16.5, WGA staining intensity is higher in mutant lenses relative to control lenses, suggesting altered fiber cell membrane composition |
