| Primary Identifier | MGI:101845 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 17215 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Predicted to be involved in DNA metabolic process. Predicted to act upstream of or within DNA replication. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; limb; myocardium layer; neural ectoderm; and retina. Orthologous to human MCM3 (minichromosome maintenance complex component 3). PHENOTYPE: Mice homozygous for a null or hypomorph alleles exhibit prenatal lethality. Fetal mice homozygous for a hypomorphic allele display anemia and replicative stress during fetal erythropoiesis. Mice heterozygous for null or hypomorph alleles display increased incidence of lymphomas. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
