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Comment :

Type  MGI:General Description  mice exposed to LPS develop septic shock lasting at least 4 days accompanied by weight loss and intestinal edema before onset of recovery unlike similarly treated wild-type mice that recover within 24 hours of exposure unlike in wild-type mice, LPS exposure leads to extensive damage in multiple organs including the ileum, kidney, and liver LPS-exposed mice exhibit increased plasma lactate dehydrogenase, aspartate and alanine aminotransferase, and blood nitrogen urea compared to similarly treated wild-type mice