| First Author | Brooks BR | Year | 1978 |
| Journal | Arch Neurol | Volume | 35 |
| Issue | 9 | Pages | 590-1 |
| PubMed ID | 210748 | Mgi Jnum | J:6029 |
| Mgi Id | MGI:54506 | Doi | 10.1001/archneur.1978.00500330038007 |
| Citation | Brooks BR, et al. (1978) Decreased spinal cord cGMP in murine (wobbler) spontaneous lower motor neuron degeneration. Arch Neurol 35(9):590-1 |
| abstractText | Of the secondary messengers, cyclic quanosine monophosphate, but not cyclic adenosine monophosphate, was reduced by 80% in the cervical spinal cord and by 56% in the cerebellum of clinically affected homozygote wobbler mice compared to sex- and age-matched litter-mate clinically unaffected control mice. A neurotransmitter, gamma aminobutyric acid, and high-energy intermediates, adenosine triphosphate and phosphocreatine, were not significantly different in affected or unaffected mice. |
