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Allele : Pfn1<tm1Wit> profilin 1; targeted mutation 1, Walter Witke

Primary Identifier  MGI:2183296 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pfn1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Disruption of the locus was achieved by the insertion of a neomycin selection cassette at the start codon. Western blot analysis of thymocyte lysates showed a reduction in protein levels of approximately 50% in heterozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • pfn1<ko>,
  • pfn1<ko>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele