Primary Identifier | MGI:2183296 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pfn1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Disruption of the locus was achieved by the insertion of a neomycin selection cassette at the start codon. Western blot analysis of thymocyte lysates showed a reduction in protein levels of approximately 50% in heterozygous mutant mice. |