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Protein Coding Gene : Cstf2t cleavage stimulation factor, 3' pre-RNA subunit 2, tau
Primary Identifier  MGI:1932622 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  83410
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables RNA binding activity. Predicted to act upstream of or within mRNA 3'-end processing. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in brain and spinal cord. Orthologous to human CSTF2T (cleavage stimulation factor subunit 2 tau variant).
PHENOTYPE: Male mice homozygous for a targeted null allele are infertile due to low sperm counts, significant developmental defects in spermiogenesis, and variable abnormalities in epididymal sperm morphology and motility consistent with oligoasthenoteratozoospermia. Homozygous null females are fertile. [provided by MGI curators]
  • synonyms:
  • expressed sequence C77975,
  • 64kDa,
  • Cstf2t,
  • tCstF-64,
  • MGI:2147783,
  • C77975,
  • cleavage stimulation factor, 3' pre-RNA subunit 2, tau
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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8 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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