| First Author | Kosik KS | Year | 1988 |
| Journal | Neuron | Volume | 1 |
| Issue | 2 | Pages | 127-32 |
| PubMed ID | 3272162 | Mgi Jnum | J:10328 |
| Mgi Id | MGI:58781 | Doi | 10.1016/0896-6273(88)90196-1 |
| Citation | Kosik KS, et al. (1988) Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human. Neuron 1(2):127-32 |
| abstractText | The growth-associated protein (GAP-43) is considered a crucial component of an effective regenerative response in the nervous system. Its phosphorylation by protein kinase C correlates with long-term potentiation. Sequence analysis of human cDNAs coding for this protein shows that the human GAP-43 gene is highly homologous to the rat gene; this homology extends into the 3'-untranslated region. However, the human protein contains a 10 amino acid insert. Somatic cell hybrids demonstrate localization of the GAP-43 gene to human chromosome 3 and to mouse chromosome 16. |
