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Protein Coding Gene : Cela2a chymotrypsin-like elastase family, member 2A

Primary Identifier  MGI:95316 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  13706
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Located in collagen-containing extracellular matrix. Is expressed in bone marrow; liver; pancreas; and pancreatic acinus. Human ortholog(s) of this gene implicated in abdominal obesity-metabolic syndrome 4. Orthologous to several human genes including CELA2A (chymotrypsin like elastase 2A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered cardiac sympathovagal balance, reduced heart rate, and decreased cardiac output, stroke volume and heart ventricular size. [provided by MGI curators]
  • synonyms:
  • Cela2a,
  • elastase 2,
  • chymotrypsin-like elastase family, member 2A,
  • Ela-2,
  • Ela2a,
  • MGD-MRK-9352,
  • elastase 2A,
  • Ela2,
  • MGD-MRK-9355

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For