Primary Identifier | MGI:6389818 | Allele Type | Transgenic |
Attribute String | Epitope tag, Humanized sequence, Inserted expressed sequence | Gene | Tg(Camk2a-MAPT*P301L)#Atak |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human 4 repeat tau containing the P301L mutation and myc and FLAG tags at the N- and C-terminals, respectively, is under the control of the Camk2 promoter. The pound symbol (#) is used when line is not specified and/or lines are pooled. Mice show a 3-5-fold overexpression of the mutant tau relative to endogenous mouse tau. |