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Protein Coding Gene : Polr3b polymerase (RNA) III (DNA directed) polypeptide B
Primary Identifier  MGI:1917678 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  70428
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA-directed 5'-3' RNA polymerase activity; DNA/RNA hybrid binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase III activity. Predicted to be involved in positive regulation of innate immune response; positive regulation of interferon-beta production; and snRNA transcription by RNA polymerase III. Predicted to act upstream of or within defense response to virus and innate immune response. Predicted to be located in cytoplasm. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease and hypomyelinating leukodystrophy 8. Orthologous to human POLR3B (RNA polymerase III subunit B).
  • synonyms:
  • expressed sequence C85372,
  • polymerase (RNA) III (DNA directed) polypeptide B,
  • RIKEN cDNA A330032P03 gene,
  • RIKEN cDNA 2700078H01 gene,
  • A330032P03Rik,
  • RPC2,
  • 2700078H01Rik,
  • MGI:2443266,
  • Polr3b,
  • C85372,
  • MGI:2143941
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Features --> Cross References

Genome

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0 CDSs

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1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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