Primary Identifier | IPR012908 | Type | Family |
Short Name | PGAP1-like |
description | The sequences found in this family are similar to PGAP1 (). This is an endoplasmic reticulum membrane protein with a catalytic serine-containing motif that is conserved in a number of lipases. PGAP1 functions as a GPI inositol-deacylase; this deacylation is important not only for the efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi body but also for efficient degradation of misfolded GPI-anchored proteins in the ER [, ]. |