| Primary Identifier | MGI:109248 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 213788 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Acts upstream of or within dopamine transport and transmission of nerve impulse. Predicted to be located in postsynaptic membrane. Predicted to be active in dendrite; plasma membrane; and synapse. Is expressed in central nervous system and retina. Orthologous to human CHRM5 (cholinergic receptor muscarinic 5). PHENOTYPE: Homozygotes for a targeted null allele exhibit loss of acetylcholine-induced dilation of cerebral arteries, decreased pilocarpine-induced salivation, increased water-deprivation induced drinking, and attenuated morphine reinforcement and withdrawal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
