| Type | MGI:General | Description | 4 month old heterozygous females and males survived 33.3% and 18.2% longer, respectively, when exposed to 80% oxygen compared to wild-type mice when exposed to 80% oxygen survival of ovariectomized heterozygous females is decreased and survival of estradiol (E2) treated heterozygous males is increased compared to untreated gender matched heterozygotes dietary restriction (65% of ad libitum) further increases the survival time of heterozygous males and females kept in 80% oxygen |
