|  Help  |  About  |  Contact Us

Protein Domain : Small G protein signalling modulator 1/2, Rab-binding domain

Primary Identifier  IPR021935 Type  Domain
Short Name  SGSM1/2_RBD
description  This domain adopts a PH-like fold. It has been called the Rab-binding domain (RBD) []. Small G-protein signalling modulator 1/2 (also known as RUTBC2/1) bind to Rab9A via their Pleckstrin homology (PH) domain [, ]. RUTBC1 stimulates GTP hydrolysis by Rab32 and Rab33B [], while RUTBC2 appears to be a GAP for Rab36, Rab9A and associated proteins controling the recycling of mannose-6-phosphate receptors from late endosomes to the trans-Golgi [, , ].

1 Child Features

0 Parent Features

17 Protein Domain Regions