Primary Identifier | IPR021935 | Type | Domain |
Short Name | SGSM1/2_RBD |
description | This domain adopts a PH-like fold. It has been called the Rab-binding domain (RBD) []. Small G-protein signalling modulator 1/2 (also known as RUTBC2/1) bind to Rab9A via their Pleckstrin homology (PH) domain [, ]. RUTBC1 stimulates GTP hydrolysis by Rab32 and Rab33B [], while RUTBC2 appears to be a GAP for Rab36, Rab9A and associated proteins controling the recycling of mannose-6-phosphate receptors from late endosomes to the trans-Golgi [, , ]. |