| First Author | Koiwai O | Year | 1993 |
| Journal | Gene | Volume | 125 |
| Issue | 2 | Pages | 211-6 |
| PubMed ID | 8096488 | Mgi Jnum | J:4311 |
| Mgi Id | MGI:52807 | Doi | 10.1016/0378-1119(93)90331-v |
| Citation | Koiwai O, et al. (1993) Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene. Gene 125(2):211-6 |
| abstractText | The mouse cDNA encoding DNA topoisomerase I (TopoI) was cloned and the nucleotide sequence of 3512 bp was determined. The cDNA clone contained an open reading frame encoding a protein of 767 amino acids (aa), which is 2 aa longer than its human counterpart. Overall aa sequence homology between the mouse and human, and between the mouse and yeast (Saccharomyces cerevisiae) sequences was 96% and 42%, respectively. The mouse TopI gene was mapped at position 54.5 on chromosome 2 from linkage analyses of a three-point cross test with Geg, Ada, and a as marker genes. |
