| Primary Identifier | MGI:1919543 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 72293 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including enzyme binding activity; growth factor binding activity; and myosin heavy chain binding activity. Predicted to be involved in several processes, including negative regulation of canonical Wnt signaling pathway; positive regulation of protein localization to plasma membrane; and positive regulation of proteolysis. Predicted to act upstream of or within Wnt signaling pathway and exocytosis. Predicted to be located in basolateral plasma membrane; exocytic vesicle; and lateral plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; nasal cavity epithelium; and reproductive system. Orthologous to human NKD2 (NKD inhibitor of WNT signaling pathway 2). PHENOTYPE: Mice homozygous for a reporter allele are viable and fertile but show a slight and background-sensitive reduction in average litter size relative to control mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
